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《疑难皮肤病彩色图谱》第3版

内容提要

本书分四篇介绍了循证皮肤病学基本概念、批判性评价工具箱、各类相关皮肤疾病的循证医学运用和循证皮肤病学的未来发展。重点阐述了六大类相关皮肤疾病的证据,包括常见炎症性皮肤病,皮肤肿瘤、痣与光线性角化病,感染性皮肤病、皮疹及寄生虫感染,色素性疾病,常见的损容性皮肤病和其他重要皮肤病。本书采用最新的循证医学方法对皮肤科常见疾病做出了内容翔实、证据丰富、决策明确的记录,是各级临床皮肤科医生的必备参考书。

《疑难皮肤病彩色图谱》证书

朱文元教授

作者简介

朱文元,1960年上海第一医学院医学系毕业,同年至北京协和医院皮肤科工作。1966年起在南京医科大学第一附属医院皮肤科工作。现任皮肤科主任医师、教授、博士生导师,《临床皮肤科杂志》主编,美国皮肤病杂志Archives of Dermatology国际编委。国内5种专业期刊编委,亚洲色素细胞研究会理事。1989~1991年在美国迈阿密大学医学院作高级访问学者。发表论文近300篇,英文论文49篇。主编《荨麻疹》、《白癜风与黄褐斑》、《痤疮》、《毛发疾病》等专著7部,参编《Cosmetic Formulation of Skin Care Products》等书8部,主审《现代皮肤性病学进展》等专著3部。承担国家、部和省级科研课题16项,黑素细胞研究3次获国家自然科学基金资助。获省、厅科技进步奖7项。“外阴部脂溢性角化病含人乳头瘤病毒”获美国皮肤科学会金质奖。指导博士研究生15名。1992年享受国务院特殊津贴,荣获江苏省有特殊贡献专家和高校先进工作者称号。1998年被评为全国优秀教师,2000年被评为江苏省优秀研究生导师。2004年《临床皮肤科杂志》荣获江苏省期刊一等奖,全国二等奖。

倪容之教授

倪容之,历任南京军区南京总医院皮肤科主任、主任医师、教授。南京大学医学院临床学院教授,上海第二军医大学兼职教授。中华医学会江苏省皮肤科分会副主任委员、中西医结合学会江苏省皮肤科分会副主任委员、江苏省制冷学会常务理事、解放军医学科学委员会皮肤科学会常委。南京军区医学科学委员会委员兼皮肤科专业组组长。《临床皮肤科杂志》副主编、《中华皮肤科杂志》常务编委、《中国皮肤性病学杂志》编委、《美中皮肤科杂志》编委、《人民军医》杂志特约编委。主编的专著有《现代皮肤病治疗学》、《药疹》,参加编写著作8本。曾获国家卫生部三等奖、江苏省科技成果三等奖、南京军区科技成果三等和四等奖。荣立三等功1次,曾被授予“军中名老医学专家”称号。

第3版前言

《疑难皮肤病彩色图谱》出版后深受广大医师好评,2008年获中国新闻出版总署“三个一百”原创图书出版工程奖。在第2版中,我们删除了部分重复和一般的皮肤病。新增加疑难皮肤病125种,图片317张。第3版图谱共有疑难皮肤病475种,图片1383幅,并对部分图片英文说明作了修正。希望《疑难皮肤病彩色图谱》第2版能成为皮肤科医师的良师益友。光阴荏苒,皮肤病的新病种和新表现将会不断出现。我们将继续收集、整理,并把它们汇编成图谱,为皮肤病的教学任务,尽一份微薄之力。

南京医科大学第一附属医院皮肤科教授

朱文元

2017年10月

第1版序一

皮肤病的诊断与其他学科一样,都是要根据病史、体检、各种实验室检查及影像学检查等而确定。但是皮肤病的形态学在皮肤病诊断中仍然占有十分重要的地位,因此皮肤病图谱对皮肤科医师有很大的帮助,特别是一些疑难少见的皮肤病,它可起到“看图识病”的效果。

有鉴于此,朱文元教授在担任《临床皮肤科杂志》主编后,注意收集疑难与少见的皮肤病病例,并且添加了朱教授多年来积累的疑难病例,将之汇编成册,予以出版。这本书共收集疑难病例414例,图片1264帧,不仅有临床照片,同时还有组织病理、免疫组化,以及一些必要的检查,为确诊提供了依据。这些图片图像清晰,色彩逼真,印刷质量高,不失为一本高质量的图谱。它为广大皮肤科临床医师提供了一本有价值的参考书与教材。

本书的另一特点是图解说明采用中英文两种文字,并且同时向国外发行。这在国内出版的图书中还是首次。它可使国外的皮肤科医师对我国的皮肤病有所了解,从而扩大了国际间的学术交流,也增进了与国外皮肤科医师间的相互了解,有利于我国皮肤科事业的进步与发展。

我对朱文元教授和倪容之教授主编的这部图谱的出版表示祝贺。

中国医学科学院皮肤病研究所 徐文严教授

第1版序二

我一直热切盼望着这本关于中国皮肤疾病的重要图书的出版。对西方皮肤病医生而言,中国人群的皮肤结构和皮肤疾病在很大程度上仍是个未知数。我们相信所有的常见病都会出现在这个人口众多和多样化的民族中,此外必定还有许多常见病的少见变异型以及罕有病种的存在,而在中国以外的地方少见或不为所知。这本图谱将告诉我们期待已久的中国人群的皮肤结构和皮肤疾病。近年来贸易合作的加强,旅游业的普及以及定居各地中国人群亲属间的探访活动,造成亚裔人群在美国人口比例升高,因此这本著作意义尤显重大。在与亚裔人群越来越多的接触中,西方皮肤病医生能拥有这本图册在手作为参考很有用。不仅能提高诊断能力,还能对以往不能处理的常见或少见病的病人提供新的治疗选择。因此,再次祝贺本书的出版。

Peter MElias,M.D.

美国加利福尼亚大学医学院旧金山分校皮肤科

目录

第1章病毒感染性皮肤病Viral Diseases

1新生儿单纯疱疹病毒感染Neonatal herpes simplex virus infection

2双侧带状疱疹Bilateral herpes zoster

3巨大寻常疣伴皮角 Giant verruca vulgaris associated with cutaneous horns

4外耳道乳头状瘤病Papillomatosis of external auditory canal

5鲍恩样丘疹病Bowenoid papulosis

6非对称性近屈曲部疹Asymmetric periflexural exanthema

第2章球菌感染性皮肤病 Bacterial Infections

1富尼埃坏疽(暴发性生殖器坏疽)Fournier gangrene(Severe Fournier gangrene)

2浅表肉芽肿性脓皮病 Superficial granulomatous pyoderma

第3章杆菌感染性皮肤病Mycobacterial Diseases

1界线类偏结核样型麻风Tuberculoid borderline leprosy

2增殖性寻常狼疮Proliferative lupus vulgaris

3疣状皮肤结核Tuberculosis verrucosa cutis

4游泳池肉芽肿Swimming pool granuloma

5皮肤炭疽病Cutaneous anthrax

6窝状角质松解症Pitted keratolysis

第4章衣原体及立克次体感染性皮肤病Chlamydiae Diseases

1Reiter综合征 Reiter’s syndrome

第5章真菌感染性皮肤病 Diseases Resulting from Fungi and Yeasts

1成人不典型黄癣Adult atypical favus

2猪小孢子菌引起的脓癣 Kerion caused by Microsporum nanum

3红色毛癣菌致股癣合并龟头癣Tinea cruris and tinea of glans penis caused by

Trichophyton rubrum

4红色毛癣菌肉芽肿Trichophyton rubrum granuloma

5皮肤播散性红色毛癣菌病Diffused dermatophytosis resulting from trichophyton

rubrum

6掌黑癣Tinea manuum nigra

7花斑癣Tinea versicolor

8皮肤念珠菌性肉芽肿合并念珠菌性颈淋巴结炎Skin candidal granuloma

complicated by candidal cervical lymphadenitis

9慢性皮肤黏膜念珠菌病Chronic mucocutaneous candidiasis

10原发性皮肤隐球菌病Primary cutaneous cryptoccosis

11皮肤隐球菌病Cutaneous cryptococcosis

12传染性软疣样皮损表现的播散性隐球菌病Disseminated cryptococcosis

resembling molluscum contagiosum

13表现为皮肤溃疡和骨髓炎的播散性隐球菌病Disseminated cryptococcosis

with multiple cutaneous lesions and osteomyelitis

14多发结节表现的孢子丝菌病Sporotrichosis manifesting in the form of polynodulus

15淋巴管型着色芽生菌病Chromoblastomycosis with lymphatic spread

16蛙粪霉病Basidiobolomycosis

17手部放线菌病Hand actinomycosis

18中型原藻病Zopfii protothecosis

19奴卡菌性足菌肿Mycetoma caused bynocardia brasiliensis

20多变根毛霉引起原发皮肤毛霉病Primary cutaneousmycormycosis caused by

Rhizomucor variabilis

21皮肤链格孢霉病Cutaneous alternariosis

22镰刀菌皮肤肉芽肿Skin Fusarium spgranuloma

23腋毛菌病 Trichomycosis axillaris

第6章寄生虫、昆虫及动物性皮肤病

Parasitic Infestations,Stings,and Bites1皮肤利什曼病Leishmaniasis cutis

2皮肤并殖吸虫病Skin distoma paragonimiasis

3匍行疹Creeping eruption

4皮肤、脑猪囊虫病Cysticercosis cutis and brain

5牛皮蝇幼虫所致皮肤蝇蛆病Cutaneous Myiasis caused by larvae of Hypoderma bovis

6眼睑虱病 Phthiriasis palpebrarum

7蜱叮咬Tick bite

8结痂性疥疮(挪威疥)Norwegian scabies

9婴儿蒲螨皮炎Infant pyemotes dermatitis

10水母皮炎Jellyfish dermatitis

第7章性传播性疾病 Sexually Transmitted Diseases

1多发性硬下疳Multiple chancre

2环形疹、扁平湿疣共存的二期梅毒Secondary syphilis presented with annular syphilid and condyloma latum

3结节性二期梅毒疹Secondary syphilis with nodular lesion

4环状红斑样二期梅毒疹Annular erythema secondary syphilis

5梅毒性脱发Syphilitic alopecia

6扁平型生殖器疣Flat condyloma

第8章物理性疾病 Dermatoses Resulting from Physical Factors

1火激红斑Erythema abigne

2光化性扁平苔藓Actinic lichen planus

3植物光皮炎Phytophotodermatitis

4植物光皮炎伴手指坏疽Phytophotodermatitis with digital gangrene

5野胡萝卜煎剂引起的植物日光性皮炎Phytophotodermatitis due to wild carrot decoction

6中药煎剂引起的植物日光性皮炎Phytophotodermatitis due to Chinese herbal

medicine decoction

7胶样粟丘疹Colloid milium

8人工皮炎Factitious dermatitis (Dermatitis artefacta)

第9章变态反应性皮肤病 Hypersensitivity Diseases

1形态罕见的刺激性接触性皮炎Irritant contact dermatitis with rare type of skin

lesion

2芒果皮炎Mango dermatitis

3水芹菜引起的接触性皮炎 Contact dermatitis caused by bengal waterdropwort

herb

4Blaschko皮炎Blaschko dermatitis

5创伤后湿疹Posttraumatic eczema

6晕皮炎Halo dermatitis

7记忆性荨麻疹Recall urticaria

8大疱性荨麻疹Bullous urticaria

9妊娠瘙痒性荨麻疹性丘疹斑块Pruritic urticarial papules and plaques of pregnancy

10泛发性固定性药疹Extensive fixed drug eruption

11环形固定性药疹Annular fixed drug eruption

12掌跖部无色素沉着型固定性药疹Nonpigmenting fixed drug eruptions affecting

the palms and soles

13氨苯砜综合征Dapsone hypersensitivity syndrome

第10章职业性皮肤病Occupational Disease

1职业性疣赘Occupational neoplasm

第11章结缔组织病 Connective Tissue Diseases

1环状红斑型亚急性皮肤型红斑狼疮Annular erythematous type subacute

cutaneous lupus erythematosus

2大疱性系统性红斑狼疮Bullous systemic lupus erythematosus

3肿胀性红斑狼疮Lupus erythematosus tumidus

4新生儿红斑狼疮Neonatal lupus erythematosus

5抗磷脂抗体综合征Antiphospholipid syndrome

6结节性(假肉瘤性)筋膜炎Nodular (pseudosarcomatous) fasciitis

7对侧萎缩合并皮肤斑状萎缩 Crossed total hemiatrophy associated with

atrophoderma of PasiniPierini

8萎缩性肢端皮炎Acrodermatitis atrophicans

9Moulin线状皮肤萎缩Linear atrophoderma of Moulin

10带状分布的皮肤萎缩 Atrophoderma of Pasini and Pierini in zosteriform

distribution

11巨大型和多发型斑状皮肤萎缩 Atrophoderma of Pasini and Pierini: multiple

and giant

12类风湿嗜中性皮炎Rheumatoid neutrophilic dermatitis

13结节性皮肤狼疮性黏蛋白病 Nodular cutaneous lupus mucinosis

第12章与皮肤有关的免疫缺陷病

Skin Related Immunodeficiency Disorder1先天性胸腺发育不良Congenital thymic dysplasia

2移植物抗宿主病 Graftversushost disease

第13章角化性皮肤病Keratoderma

1角化过度型汗孔角化症Hyperkeratotic porokeratosis

2偏侧性汗孔角化症Porokeratosis localized on the left side of the body

3汗孔角化症合并假性阿洪病Pseudoainhum with porokeratosis of Mibelli

4播散性浅表性光线性汗孔角化症Disseminated superficial actinic porokeratosis

5点状掌跖角皮症Punctate palmoplantar keratoderma

6条纹状掌跖角皮症Striated palmoplantar keratoderma

7棘状角皮症Spiny keratoderma

8表皮松解性掌跖角化病Epidermolytic palmoplantar keratoderma

9疣状肢端角化症Acrokeratosis verruciformis

10疣状角化不良瘤Warty dyskeratoma

11进行性对称性红斑角皮症Progressive symmetric erythrokeratodermia

12砷角化病Keratosis arsenica

13乳头乳晕角化过度症Hyperkeratosis of the nipple and areola

14光泽角化病Waxy keratosis

15肢端角化性类弹性纤维病Acrokeratoelastoidosis

16扁平苔藓样角化病Lichen planuslike keratosis

17水源性角化症Aquagenic acrokeratoderma

第14章红斑性皮肤病Erythematous Disease

1匍形性回状红斑Erythema gyratum repens

2可触及游走性弧形红斑 Palpable archiform migratory erythema

3掌跖疼痛性红斑为首发表现的左心房黏液瘤Left atrial myxoma presenting with

painful erythematous macules on the palms and soles

4复发性疼痛性红斑Recurrent painful erythema

5复发性半环状丘疹和红斑Erythema papulosa semicircularis recidivans

6红色阴囊综合征Red scrotum syndrome

第15章丘疹鳞屑性皮病Papule and Scale Diseases

1掌跖银屑病Palmoplantar psoriasis

2反向银屑病Inverse psoriasis

3急性痘疮样苔藓状糠疹Pityriasis lichenoides et varioliformis acuta

4紫癜型玫瑰糠疹Purpuric pityriasis rosea

5泛发性丘疹型玫瑰糠疹Pityriasis rosea

6色素性玫瑰糠疹 Pigmentary pityriasis rosea

7鳞状毛囊角化症(土肥)Keratosis follicularis squamosa (Dohi)

8面部鳞状毛囊角化病Facial keratosis follicularis squamosa

9肥厚性扁平苔藓Hypertrophic lichen planus

10毛发扁平苔藓 Lichen planopilaris

11色素性扁平苔藓Lichen planus pigmentosus

12皱褶部色素性扁平苔藓Lichen planus pigmentosusinversus

13色素性扁平苔藓沿小腿静脉分布Supravenous lichen planus pigmentosus on

the leg

14线形色素性扁平苔藓Linear lichen planus pigmentosus

15 20甲扁平苔藓Lichen planus of nails

16扁平苔藓合并白癜风Coincidence of lichen planus and vitiligo

17急性泛发性扁平苔藓Acute generalized lichen planus

18黑色丘疹性皮病Dermatosis papulosa nigra

19硬化性苔藓Lichen sclerosus

20非生殖器部位特殊形态硬化性萎缩性苔藓Lichen sclerosus in nongenital area

with special shape

21面颈部毛囊性红斑黑变病Erythromelanosis follicularis faciei et colli

22金色苔藓Lichen aureus

23泛发性光泽苔藓Lichen nitidus

24连圈状秕糠疹Pityriasis circinata

第16章大疱和无菌性脓疱性皮病Chronic Blistering Dermatoses

1天疱疮患儿(新生儿)Pemphigus neonatorum baby

2毛囊角化病样天疱疮Follicularis kerotosoid pemphigus

3伴限局性Castleman病的副肿瘤性天疱疮Paraneoplastic pemphigus with

Castleman’s disease

4副肿瘤性天疱疮Paraneoplastic pemphigus

5结节性类天疱疮Pemphigoid nodularis

6儿童线状IgA大疱性皮病Linear IgA bullous dermatosis of childhood

7成人线状IgA大疱性皮病Linear IgA bullous dermatosis in adult

8复发性线状棘层松解皮病Relapsing linear acantholytic dermatosis

9具有掌跖损害的外生殖器部位的棘层松解性皮病 Acantholytic dermatosis of

genitocrural area associated the lesions on the palms and soles

10获得性大疱性表皮松解症Epidermolysis bullosa acquisita

11疱疹样脓疱病并发妊娠期肝内胆汁淤积症Impetigo herpetiformis and gestational

intrahepatic cholestasis

12掌跖脓疱病合并前胸壁综合征 Pustulosis palmoplantaris accompanied with

anterior chest wall syndromes

13嗜酸性脓疱性毛囊炎Eosinophilic pustular folliculitis

14婴儿肢端脓疱病Infantile acropustulosis

15泛发性连续性肢端皮炎Generalized acrodermatitis continua

第17章真皮弹性纤维疾病 Dermal Elastic Tissue Diseases

1播散型匍行性穿通性弹性纤维病Disseminated elastosis perforans serpiginosum

2先天性皮肤松弛症Congenital cutis laxa

3全身性皮肤松弛症Generalized elastorrhexis

4局限性皮肤松弛症Circumscribed cutis laxa

5眼睑松弛症Blepharochalasis

6弹性纤维性假黄瘤Pseudoxanthoma elasticum

7皮肤弹性过度伴免疫学检查异常Cutis hyperelastica complicated by the abnormity

in immunoassay

8巨大结缔组织痣Giant connective tissue nevus

9发疹性皮肤胶原瘤Eruptive collagenoma of the skin

10颈部白色纤维丘疹病White fibrous papulosis of the neck

第18章萎缩性皮肤病 Atrophy Diseases

1膨胀纹和局限性萎缩 Striae distensae and localized atrophy

2原发性斑状萎缩Macular atrophy

3包皮假性阿洪病Pseudoainhun of the penis

第19章皮肤血管炎 Cutaneous Vasculitis

1持久性隆起红斑Erythema elevatum diutinum

2急性发热性嗜中性皮病 Sweet’s syndrome

3皮下型急性发热性嗜中性皮肤病Subcutaneous acute febrile neutrophilic

dermatosis

4 Wegener肉芽肿Wegener’s granulomatosis

5坏疽性脓皮病Pyoderma gangrenosum

6恶性萎缩性丘疹病伴肠穿孔Malignant atrophic papulosis accompanying

intestinal perforation

7青斑样血管炎Livedoid vasculitis

8血小板增多性紫癜Thrombocythemia purpura

9播散性瘙痒性血管性皮炎Disseminnate pruriginous angiodermatitis

第20章皮肤脉管性疾病 Cutaneous Vascular Diseases

1发疹性复发性色素性沉着性毛细血管扩张症 Eruptive recurrent pigmented

telangiectasia

2持久性发疹性斑状毛细血管扩张症Telangiectasia macularis eruptive perstans

3单侧性皮肤浅表毛细血管扩张症Unilateral dermatomal telangiectasia

4单侧痣样毛细血管扩张症和Bier斑Unilateral nevoid telangiectasia

superimposed on the Bier spots

5胸腹壁血栓性静脉炎Mondor’s disease (Superficial thrombophlebitis of the

chest)

6闭塞性动脉硬化症Arteriosclerosis obliterans

7发疹性假性血管瘤病 Eruptive pseudoangiomatosis

第21章皮下脂肪组织疾病 Subcutaneous Adipose Tissue Diseases

1组织细胞吞噬性脂膜炎Cytophagic histiocytic panniculitis

2硬化性脂膜炎Sclerosing panniculitis

3嗜酸细胞性脂膜炎Eosinophilic panniculitis

4全身性脂肪萎缩Total lipoatrophy

5幼儿腹部离心性脂肪营养不良Lipodystrophia centrifugalis abdominalis infantilis

第22章非感染性肉芽肿Noinfectious Granuloma

1环状肉芽肿Granuloma annulare

2儿童播散型环状肉芽肿Generalized granuloma annularein in a boy

3穿通性环状肉芽肿Perforating granuloma annulare

4播散性环状肉芽肿合并乙型肝炎病毒感染Generalized granuloma annulare

associated with the infection of chronic hepatitis B virus

5多形性肉芽肿Granuloma multiforme

6环状弹力纤维溶解性巨细胞肉芽肿Annular elastolytic giant cell granuloma

7皮肤硅石肉芽肿 Cutaneous silica granuloma

8反应性结节性增生Reactive nodular hyperplasia

第23章皮肤附属器疾病Diseases of the Skin Appendages

1鼻红粒病Granulosis rubra nasi

2 FoxFordyce病FoxFordyce disease

3蛇形斑秃Alopecia areata called ophiasis

4全秃再生发呈马蹄形、蛇形嵌合型分布Mosaic hair regrowth pattern of ophiasis

and sisaipho in a patient with alopecia totalis

5Brocq假性斑秃Brocq pseudopelade

6蛇形脱发和W形脱发嵌合分布Mosaic distribution of ophiasis and Wshaped

alopecia areata

7未累及皮损内白发的斑秃Alopecia areata sparing white hairs within lesion

8浸润性导管癌患者出现多毛和斑秃Coexistence of acquired hypertrichosis and

scalp alopecia in a patient with infiltrating ductal carcinoma

9羊毛状发Woolly hair

10念珠形发Monilethrix

11环状发Pili annulati

12结毛症Trichonodosis(Knotted hair)

13管状发鞘Hair cast

14小棘毛壅症 Trichostasis spinulosa

15皮肤匍行毛发Cutaneous pili migrans

16黄发Yellow hair

17拔须后永久性白须Permanent poliosis after plucking

18先天性厚甲症 Pachyonychia congenita

19先天性全白甲Congenital leukonychia totalis

20铅沉积黑甲Hyperpigmentation of the nail from lead deposition

21纵行红甲Longitudinal erythronychia

22甲变色Chromonychias

23甲下裂片形出血Splinter haemorrhages

24颈部皮脂腺增生Sebaceous hyperplasia of the neck

25阴囊皮脂腺增生Sebaceous gland hyperplasia on the scrotum

26老年皮脂腺过度增生Senile sebaceous hyperplasia

27烧伤后表皮内皮脂腺增生Sebaceous hyperplasia within epidermis after scald

第24章内分泌障碍性皮肤病Endocrine Skin Diseases

1胫前黏液性水肿Pretibial myxedema

2皮肤钙质沉着症Calcinosis cutis

3阴囊特发性皮肤钙沉着症Idiopathic calcinosis of the scrotum

4单侧痣样黑棘皮病Unilateral nevoid acanthosis nigricans

5恶性黑棘皮病Malignant acanthosis nigricans

6恶性黑棘皮病合并胃贲门腺癌Malignant acanthosis nigricans complicated by

gastric adenocarcinoma

7高雄激素血症胰岛素抵抗黑棘皮病综合征Hyperandrogenism,insulin resistance

and acanthosis nigricans syndrome

8坏死松解游走性红斑与胰高糖素瘤综合征Necrolytic migratory erythema

(Glucagonoma syndrome)

第25章代谢、营养障碍性皮肤病

Metabolic and Nutritional Skin Diseases1结节性黄瘤病并发主动脉瓣狭窄Tuberous xanthoma associated with aortic

stenosis

2播散性黄瘤Xanthoma disseminatum

3类脂蛋白沉积症Lipoid proteinosis

4类脂质渐进性坏死Necrobiosis lipoidica

5幼年性黄色肉芽肿Juvenile xanthoma (nevoxanthoendothelioma)

6面部苔藓样型幼年黄色肉芽肿Juvenile xanthogranuloma with lichenoid

appearance

7渐进性坏死性黄色肉芽肿Necrobiotic xanthogranuloma

8成人单发黄色肉芽肿Solitaty adult xanthogranuloma

9先天性红细胞生成性卟啉病Congenital erythropoietic porphyria

10皮肤异色病样淀粉样变病Poikilodermalike cutaneous amyloidosis

11结节型皮肤淀粉样变性Nodular amyloidosis

12黏液水肿性苔藓Lichen myxedematosus

13硬化性黏液水肿性苔藓Scleromyxedema

14毛囊黏蛋白病Follicular mucinosis

15网状红斑黏蛋白病Reticular erythematous mucinosis

16皮肤局灶性黏蛋白病Cutaneous focal mucinosis

17肢端持续性丘疹性黏蛋白沉积症Acral persistent popular mucinosis

18烟酸缺乏症Pellagra

19胡萝卜素血症Carotenemi

20糖原贮积病Ⅰ型Type Ⅰglycogenosis

21褐黄病Ochronosis

第26章色素障碍性皮肤病Disturbances of Pigmentation

1色素型分界线Pigmentary demarcation lines

2黄褐斑 Melasma

3泛发性雀斑样痣病Generalized lentiginosis

4多发性黑子综合征Multiple lentigines syndrome (LEOPARD syndrome)

5补骨脂素长波紫外线雀斑样痣PUVA lentigo

6非典型阴茎雀斑样痣Atypical penile lentigo

7巨大先天性黑素细胞痣Giant congenital melanocytic nevus

8太田痣 Nevus of Ota

9太田痣合并鲜红斑痣Nevus Ota associated with nevus flammeus

10伊藤痣Naevus of Ito

11伊藤痣上继发白斑(集晕痣与晕皮炎现象于一体)Partial depigmentation arised

in the Nevus of Ito:the halo nevus and halo dermatitis in the same patient

12面部褐青色痣Acquired bilateral nevus of Otalike macules

13Becker痣中并发痤疮Acne vulgaris superimposed on the Becker’s nevus

14双侧分布的色素性毛皮痣合并颈部白色纤维丘疹病 Bilateral Becker nevus

associated with white fibrous papulosis of the neck

15Becker 综合征Becker’s syndrome

16神经皮肤黑变病Neurocutaneous melanosis

17进行性肢端黑变病Acromelanosis progressive

18眶周黑皮病Periobital melanosis

19北村网状肢端色素沉着症Reticulate acropigmenttion of Kitamura

20大疱性先天性皮肤异色症Congenital poikiloderma with bullae

21皱褶部网状色素沉着症DowlingDegos disease

22遗传性对称性色素异常症并发掌跖角化病Dyschromatosis symmetrical

hereditaria with palmoplantar keratoderma

23家族性进行性色素沉着Familial progressive hyperpigmentation

24家族进行性色素沉着和色素减退Familial progressive hypoand

hyperpigmentation

25遗传性泛发性色素异常症Dyschromatosis universalis hereditaria

26伴巨大黑素小体表现的遗传性对称性色素异常症Hereditary symmetrical

dyschromatosis with melanin macroglobules

27线状和旋涡状痣样过度黑素沉着病Linear and whorled nevoid hypermelanosis

28点彩样色素沉着斑Pointillist melanotic macules

29获得性真皮黑素细胞增生症 Acquired dermal melanocytosis

30意外粉粒沉着病Accidental tattoos

31波纹状融合性网状乳头瘤Rippling lesions of confluent and reticulated

papillomatosis

32先天性巨大色素痣并发白癜风Giant congenital pigmented nevus complicated

with vitiligo

33三色白癜风Trichrome vitiligo

34节段型五色白癜风Pentachrome vitiligo in a segmental pattern

35炎症性白癜风Inflammatory vitiligo

36儿童无色素性痣Nevus depigmentosus in children

37星状自发性假癜Stellate spontaneous pseudoscars

第27章先天性、遗传性皮病 Genodermatoses

1色素失禁合并不完全唇裂 Incontinentia pigmenti with unilateral complete cleft

lip

2色素失禁伴乳房发育不良 Incontinentia pigmenti associated with an undeveloped

breast

3家族性慢性良性天疱疮Familial chronic benign pemphigus

4单纯型大疱性表皮松解症:WeberCockayne亚型Epidermolysis bullosa simplex:

WeberCockayne

5常染色体隐性遗传的HallopeauSiemens型营养不良型大疱性表皮松解症

HallopeauSiemens type of recessive dystrophic epidermolysis bullosa

6胫前大疱性表皮松解症Pretibial epidermolysis bullosa

7痒疹样显性遗传营养不良型大疱性表皮松解症Prurigolike inherited epidermolysis

bullosa

8Siemens大疱性鱼鳞病Ichthyosis bullosa of Siemens

9表皮松解性角化过度 (大疱性先天性鱼鳞病样红皮病)Epidermolytic

hyperkeratosis (Bullous congenital ichthyosiform erythroderma)

10表皮松解性角化过度鱼鳞病伴侏儒Epidermolytic hyperkeratosis ichthyosis

complicated by dwarf

11火棉胶婴儿Collodion baby

12先天性角化不良Dyskeratosis congenita

13残留性多指症Rudimentary polydactyly

14骨膜增生厚皮症Pachydermoperiostosis

15先天性皮肤缺损Congenital localized absence of skin

16婴儿肢端纤维瘤病Infantile digital fibromatosis

17掌跖多发性皮肤纤维瘤Dermatofibroma

18着色性干皮病继发恶性肿瘤Carcinomas in patients with xeroderma pigmentosa

19棘状秃发性毛发角化症Keratosis follicularis spinulosa decalvans

20幼年透明蛋白纤维瘤病Juvenile hyaline fibromatosis

21小斑片三色皮肤征Cutis tricolor parvimaculata

22丘疹性弹力纤维离解Papular elastorrhexis

第28章黏膜及黏膜皮肤交界处疾病

Disorders of the Mucous Membranes1梅尔克松罗森塔尔综合征MelkerssonRosenthal syndrome

2浆细胞性唇炎Plasma cell cheilitis

3阴茎硬化性淋巴管炎Sclerosing lymphangiitis

第29章皮肤肿瘤 Tumors of the Skin

一、表皮肿瘤Epidermal Tumors

1棘层松解性角化不良表皮痣Acantholytic dyskeratotic epidermal nevus

2棘层松解角化不良性表皮痣并发色素性毛表皮痣Acantholytic dyskeratotic

epidermal naevus complicated by pigmented hairy epidermal naevus

3泛发性表皮痣Epidermal nevus

4黑头粉刺痣Comedo naevus

5表皮痣综合征Epidermal nevus syndrome

6多发性小丘疹脂溢性角化病Multiple small papular seborrheic keratosis

7放线型分布的脂溢性角化病Seborrheic keratosis distributed along skin cleavage

lines

8雨滴状脂溢性角化症Raindroplike seborrheic keratoses

9脂溢性角化病和卵状糠秕马拉色菌 Seborrheic keratosis and pityrosporum ovale

10大细胞棘皮瘤Large cell acanthoma

11巨大皮角Giant cutaneous horn

12发疹性毳毛囊肿Eruptive vellus hair cyst

13Pinkus纤维上皮瘤Fibroepithelioma of Pinkus

14Pinkus纤维上皮瘤合并基底细胞癌Fibroepithelioma of Pinkus associated with

basal cell carcinoma

15多发性角化棘皮瘤Multiple keratoacanthoma

16鲍温病Bowen’s disease

17多发性鲍温病Multiple Bowen’s disease

18生殖器Paget病Genital Paget’s disease

19疣状表皮发育不良继发基底鳞状细胞癌和多发性纤维毛囊瘤Epidermodysplasia

verruciformis associated with basal squamous cell carcinoma and multiple

fibrofolliculoma

20浅表性基底细胞上皮瘤Superficial basal cell epithelioma

21毛囊漏斗形基底细胞癌 Infundibulocystic basal cell carcinoma

22慢性放射性皮炎继发鳞状细胞癌Chronic radiodermatitis secondary squamous

cell carcinoma

23皮肤透明细胞鳞状细胞癌 Cutaneous clear cell squamous cell carcinoma

24双侧斑块型粟丘疹Bilateral milia en plaque

25外耳道内斑块型粟丘疹Milia en plaque in bilateral auricular canals

26多发性发疹性粟丘疹Multiple eruptive milia

27四黑头扩张孔Dilated pore with four comedos

28倒置性毛囊角化病Inverted follicular keratosis

二、皮肤附属器肿瘤Tumors of the Epidermal Appendages

30皮脂腺痣Facial nevus sebaceous

31皮脂腺痣合并大汗腺囊腺瘤Nevus sebaceus with apocrine cyst adenoma

32乳晕皮脂腺增生Sebaceous hyperplasia around nipple

33线状皮脂腺痣综合征Linear nevus sebaceous syndrome

34大汗腺囊瘤Apocrine hidrocystoma around nipple

35恶性小汗腺汗孔瘤Malignant eccrine poroma

36带状疱疹样分布的多发性小汗腺螺旋腺瘤 Multiple eccrine spiradenomas in a

linear or zosteriform distribution

37汗管瘤合并粟丘疹Syringoma associated with miliumlike lesions

38发疹型汗管瘤Eruptive syringoma

39粟丘疹样表现的外阴汗管瘤Milialike syringoma

40泛发性发疹性透明细胞汗管瘤 Generalized eruptire clearcell syringoma

41乳头状汗管囊腺瘤Syringocystadenoma papilliferum

42鼻翼部毛囊瘤Trichofolliculoma

43微囊肿性附属器癌Microcystic adnexal carcinoma

44孤立性毛发上皮瘤Solitary trichoepithelioma

45多发性毛发上皮瘤Multiple trichoepitheliomas

46水疱型钙化上皮瘤Calcifying epithelioma with a bulla appearance

47结缔组织增生性毛发上皮瘤Desmoplastic trichoepithelioma

48小汗腺血管样错构瘤Eccrine angiomatous hamartoma

49透明细胞汗腺瘤Clear cell hidradenoma

50乳头状汗管囊腺瘤Syringocytadenoma papilliferum

51乳头状汗管囊腺瘤并发基底细胞上皮瘤Syringocystadenoma papilliferum

complicated by basal cell epithelioma

三、结缔组织肿瘤Tumors of Fibrous Tissue

52上皮样组织细胞瘤Epithelioid cell histiocytoma

53发疹性组织细胞瘤Eruptive histiocytomas

54多中心网状组织细胞增生症Multicentric reticulohistiocytosis

55以多发残毁性关节炎为显著表现的多中心网状组织细胞增生症Multicentric

reticulohistiocytosis with arthritis multilans

56勒雪病LettererSiwe disease

57发疹性朗格汉斯细胞组织细胞增生症Exanthematous Langerhans cell

histiocytosis

58播散型Paget病样网状细胞增生病Disseminated pagetoid reticulosis

59上皮样肉瘤Epithelioid sarcoma

60结节性(假肉瘤性)筋膜炎Nodular (pseudosarcomatous) fasciitis

61先天性隆突性皮肤纤维肉瘤Congenital dermatofibrosarcoma protuberans

62萎缩斑块样隆突性皮肤纤维肉瘤Atrophic and plaquelike dermatofibrosarcoma

protuberans

63获得性指(趾)部纤维角化瘤Acquired digital fibrokeratoma

四、脉管组织肿瘤Tumors of Vascular Tissue

64色素血管性斑痣性错构瘤病Phakomatosis pigmentovascularis

65匍行性血管瘤Angioma serpiginosum

66反应性血管内皮细胞瘤病 Reactive angioendotheliomatosis

67微静脉性血管瘤Microvenular hemangioma

68梭形细胞血管瘤Spindle cell hemangioma

69上皮样血管瘤Epithelioid hemangioma

70疣状血管瘤Verrucous haemangioma

71丛状血管瘤Tufted angioma

72浅表性血管黏液瘤Superficial angiomyxoma

73靶样含铁血黄素沉积性血管瘤Targetoid hemosiderotic hemangioma

74弥漫性躯体血管角化瘤Angiokeratoma corporis diffusum

75单侧阴囊血管角皮瘤Unilateral angiokeratoma on the scrotum

76女阴血管角皮瘤 Angiokeratoma on the vulva

77卡波西样血管内皮细胞瘤Kaposiform hemangioendothelioma

78恶性血管内皮细胞瘤Malignant endothelioma

79恶性血管内皮瘤合并疱疹样天疱疮Malignant hemangioendothelioma associated

with herpetiform pemphigus

80经典型Kaposi肉瘤Classic Kaposi’s sarcoma

81实体型血管球瘤Solid glomus tumor

82局限性多发性血管球瘤Localized multiple glomus tumors

83获得性渐进性淋巴管瘤Acguired progressive lymphangioma

84额面部出血性淋巴管瘤Bleeding lymphangioma on frontal plane

85弥漫性海绵状淋巴管瘤Cavernous lymphangioma

五、脂肪、肌肉和骨组织肿瘤Tumors of Fatty,Mascular and Osseus Tissue

86浅表脂肪瘤样痣Nevus lipomatosus superficialis

87硬化型浅表脂肪瘤样痣(伴脂肪组织增生的泛发型硬斑病)Nevus lipomatosus

superficialis

88甲下外生骨疣和内生软骨瘤Subungual exostosis and subungual enchondroma

89多发性皮肤平滑肌瘤Multiple leiomyoma

90皮肤平滑肌肉瘤Cutaneous leiomyosarcoma

91甲下外生骨疣Subungual exostosis

92皮肤子宫内膜异位Cutaneous endometriosis

六、神经组织肿瘤Tumors of Nerve Tissue

93皮肤Merkel细胞癌Skin Merkel cell carcinoma

94神经鞘瘤Neurilemmoma (Schwannomatosis)

95多发性神经鞘瘤Multiple neurilemmoma

96多发性栅栏状神经鞘瘤 Multiple palisaded neurolemmoma

七、色素痣和恶性黑素瘤Pigmented Nevi and Malignant Melanoma

97甲母痣恶变 Malignant transformation of nail matrix nevi

98肢端原位恶性黑素瘤Acral lentiginous melanoma

99气球状细胞恶性黑素瘤Balloon cell melanoma

100口唇恶性黑素瘤Lip malignant melanoma

101巨大先天性色素痣伴软脑膜恶性黑素瘤Giant congenital pigmented nevus with

malignant melanoma on the pia mater encephali

102肢端无色素性黑素瘤Acral amelanotic melanoma

103簇发性斯皮茨痣Agminated Spitz nevus

八、淋巴瘤和其他皮肤肿瘤Lymphoma and other Skin Tumors

104单发性肥大细胞瘤Solitary mastocytoma

105以泛发性丘疹为表现的成人肥大细胞增生病Adult mastocytosis with

generalized papules on the trunk and extremeties

106色素性荨麻疹Urticaria pigmentosa

107 Jessner 皮肤淋巴细胞浸润症Jessner’s lymphocytic infiltration of the skin

108皮肤淋巴细胞瘤Cutaneous lymphocytoma

109皮肤白血病Leukemia cutis

110真性红细胞增多症Polycythemia vera

111原发性皮肤浆细胞瘤Primary cutaneous plasmacytoma

112继发性皮肤浆细胞瘤Secondary cutaneous plasmacytoma

113皮下脂膜炎样T细胞淋巴瘤Subcutaneous panniculitislike Tcell lymphoma

114红皮病型皮肤T细胞淋巴瘤Erythrodermic cutaneous Tcell lymphoma

115牛痘样水疱病样皮肤T细胞淋巴瘤 Hydroa vacciniformelike cutaneous T cell

lymphoma

116鼻部NK/T细胞淋巴瘤Nasal natural killer/T cell lymphoma

117小腿皮肤血管内NK/T细胞淋巴瘤Cutaneous intravascular NK/T cell

lymphoma on legs

118非霍奇金淋巴瘤NonHodgkin’s lymphoma

119蕈样肉芽肿误诊为蛎壳状银屑病Mycosis fungoides misdiagnosed as psoriasis

rupioides

120以四肢色素沉着为主要表现的蕈样肉芽肿Mycosis fungoides with

hyperpigmentation on limbs

121蕈样肉芽肿继发皮肤CD30阳性大细胞淋巴瘤Mycosis fungoides associated

with cutaneous CD30 positive large Tcell lymphoma

122具有多种表现的蕈样肉芽肿Several variants of mycosis fungoides in one

patient

123以皮肤斑块浸润和肿瘤表现为主的B细胞淋巴瘤Tumorous and infiltrated

plaque variant of cutaneous Bcell lymphoma

124皮肤假性淋巴瘤Cutaneous pseudolymphoma

125皮肤窦性组织细胞增生症Cutaneous RossaiDorfman disease,or Cutaneous

sinus histocytosis

126皮肤原发性窦性组织细胞增生症Cutaneous primary sinus histiocytosis with

massive lymphadenopathy

127皮肤型RosaiDorfman病Cutaneous RosaiDorfman disease

128淋巴瘤样丘疹病 Lymphomatoid papulosis

129肺癌皮肤转移Lung cancer with skin metastasis

130胃癌皮肤转移Stomach cancer with skin metastasis

131来源于脐尿管低分化腺癌Low differentiated adenocacinoma from

umbilcourethral canal

132铠甲癌Carcinoma en cuirasse

第30章与皮肤病有关的综合征

Cutaneous Syndromes in Dermatology1Ascher综合征Ascher syndrome

2狒狒综合征Baboon syndrome

3Bloom综合征Bloom’s syndrome

4蓝色橡皮大疱性痣综合征Blue rubberbleb nevus syndrome

5息肉色素沉着脱发甲营养不良综合征CronkhiteCanada syndrome

6局灶性真皮发育不全综合征Focal dermal hypoplasia syndrome

7FavreRacouchot 综合征合并眼睑乳头状瘤FavreRacouchot syndrome associated

with eyelid papilloma

8Gorham综合征Gorham syndrome

9先天性额顶部皮下脂肪瘤胼胝体发育不良颅内脂肪瘤综合征Innate frontoparietal

subcutaneous fat oncomacallosal dysplasiaintracranial fat oncoma syndrome

10角膜炎鱼鳞病耳聋综合征Keratitisichthyosisdeafness syndrome

11外阴阴道牙龈综合征型扁平苔藓Lichen planusvulvovaginalgingival

syndrome

12JacksonLawler综合征JacksonLawler syndrome

13LaugierHunziker综合征LaugierHunziker syndrome

14Madelung综合征Madelung syndrome

15MarshallWhite综合征MarshallWhite syndrome (Bier’s Spot)

16甲、髌、肘发育不良综合征Nailwhirlboneelbow syndrome (Nailpatellaelbow

syndrome)

17Netherton综合征Netherton’s syndrome

18Olmsted 综合征Olmsted syndrome

19PapillonLefèvre综合征伴沟纹舌PapillonLefèvre syndrome with fissured tongue

20面部单侧萎缩合并颅脑病变ParryRomberg syndrome with subclinical cerebral

involvement

21先天性环状缩窄带综合征PseudoAinhum syndrome

22Proteus综合征Proteus syndrome

23色素沉着息肉综合征 Pigmentationpolyposis syndrome

24梅干腹综合征Prunebelly syndrome

25RappHodgkin综合征RappHodgkin like syndrome

26Rombo综合征Rombo syndrome

27RothmundThomson综合征RothmundThomson syndrome

28僵硬皮肤综合征 Stiff skin syndrome

29毛发鼻指趾综合征Trichorhinophalangeal syndrome

30Waardenbury综合征Waardenbury syndrome

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